B12 Folate is used in cases of: preventing B12 and folate deficiency, anemia, and regulation of red blood cell formation; assisting in metabolism of carbohydrates and fats for increased energy; maintaining the myelin sheath and protecting against peripheral and central neurological disease and aging; supporting healthy nervous, cardiovascular and immune system functioning; pre and postnatal health; enhancing brain health, memory, and learning; and finally normalizing homocysteine levels, thus decreasing risk of heart disease and stroke.