DESCRIPTION

BENEFITS

• Hypoglycemic effects via multiple mechanisms, including enhancement of insulin sensitivity
• Favourable effects on blood lipids, including a reduction in triglycerides, and both total and LDL cholesterol 9
• Activates Nrf-2, a key regulator of antioxidant gene transcription and prevention of glucose-induced neurotoxicity
• Provides 500 mg berberine HCl per capsule, the dosing strength used in clinical trials for glucose and lipid control
• Extracted from Berberis vulgaris (European barberry)
• Suitable for vegetarians/vegans 

INGREDIENTS
Medicinal Ingredients
Serving Size: 1 Vegetarian Capsule
Servings per Container: 90
Each Capsule Contains:
Berberine (Hydrochloride) (Berberis vulgaris) (root).........500 mg

Non-Medicinal Ingredients
Vegetarian capsule (cellulose, purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant), silica, stearic acid.

Allergens:
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

RECOMMENDED USE
1 capsule 2 times per day with meals or as directed by a health care practitioner. Consult a health care practitioner for use beyond 3 months.

 
WARNINGS
Consult a health care practitioner if you have leucopenia, a kidney disorder, hypotension or blood pressure problems. Consult a health care practitioner prior to use if you have hypoglycemia or diabetes. Do not use if you are pregnant or breastfeeding. May cause gastrointestinal discomfort such as constipation, vomiting, abdominal pain or diarrhea, in which case discontinue use and consult a health care practitioner. Keep out of reach of children.

Drug Interactions
Berberine has been shown to lower blood glucose levels, and may have an additive effect when combined with other hypoglycemic medications, such as metformin. Berberine has also been shown to increase levels of cylcosporin A, and combined use should be avoided.10 Berberine has demonstrated inhibitory activity on cytochrome enzymes CYP2D6, 3A4, and CYP2C9, and use of medications metabolized by these enzymes should be monitored.