Ortho·Sleep was formulated to be the most comprehensively powerful natural sleep-aid available to improve overall sleep. Ortho·Sleep is clinically proven to help increase the total sleep time (aspect of sleep quality) in people suffering from sleep restriction or altered sleep schedule such as shift-work and jet lag and helps relieve the daytime fatigue associated with jet lag. Ortho·Sleep is also clinically proven to help reduce the time it takes to fall asleep (sleep onset latency aspect of sleep quality) in people with delayed sleep phase syndrome and helps to re-set the body's sleep-wake cycle (an aspect of the circadian rhythm). A Natural Solution to Promote Restful Sleep - The most comprehensive natural sleep formula available - Helps one fall asleep stay asleep and wake up feeling refreshed - Bronze winner of the 2013 Optimyz Best of the Best Awards Amount: 2 Capsules GABA (gamma-aminobutyric acid) 100 mg L-Theanine 200 mg L-5-Hydroxytryptophan (griffonia seed) 100 mg Melatonin 3 mg Valerian root (0.8% valerenic acid) 150 mg Passionflower extract (aerial parts) 32 mg Lemon balm extract (aerial parts)* 300 mg *Cyracos is a registered trademark of Naturex Inc. Non-medicinal ingredients: maltodextrin gum Arabic silicon dioxide. Capsule: hypromellose. Suggested Use: Take 1-2 capsules before bedtime with/without food or as directed by a qualified health care practitioner. Cautions : Consult a health care practitioner prior to use if taking carbidopa or drugs/supplements with serotonergic activity. These may include but are not limited to L-tryptophan S-adenosylmethionine (SAMe) St. John's Wort antidepressants pain killers cough/cold medication containing dextromethorphan anti-nausea anti-blood pressure and anti-migraine medication. Discontinue use and consult a health care practitioner if you show signs of weakness oral ulcers or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Some people may experience gastrointestinal disturbances such as diarrhea nausea vomiting and abdominal pain as well as drowsiness. Do not use if you have scleroderma. Hypersensitivity (e.g. allergy) has been known to occur; in which case discontinue use. Do not drive or use machinery for 5 hours after taking Ortho·Sleep. Exercise caution if engaging in activities requiring mental alertness. Do not take Ortho·Sleep if pregnant nursing trying to conceive or taking immunosuppressive drugs. Not to be used by individuals under the age of 18 or those with a medical condition such as a hormonal disorder diabetes liver or kidney disease cerebral palsy seizure disorders migraine depression and or hypertension. Consult a health care practitioner if sleeplessness persists continuously for more than 3 weeks (chronic insomnia). Consult a health care practitioner if symptoms persist or worsen. Consumption with alcohol other medications or health products with sedative properties is not recommended.